Hi jazzbiker!
I start X.org normally, nothing special. What can be "special" in year 2021 to all my TC##_{x86, x86_64} is that flwm is my windows manager. I have /home/tc/.wmx with many pre-defined menu-categories (browsers, audio/video, compressors, etc) linked at start-up from ~/.X.d scripts, that is all. I do not use locales /languages settings. All is generic.
And GTK 2 or 3 are loaded only by apps (gnumeric, firefox, etc), not by me. I am stubborn on FLTK, GTK1 apps, manually added from older TC versions.