Gerald,
I believe the "urlclassifier3.sqlite" file is periodically updated from a list supplied by Google. Simply adding the file to ".xfiletool.lst " wouldn't preclude Firefox from attempting to update the file and the inherent filesystem activity overhead associated with Firefox updating the file. If Firefox cannot write to the file, there should not be any such activity.
However, my fears about file activity may be unfounded and adding the file to ".xfiletool.lst" may work equally as well, and it is certainly simpler to do it that way.
Regards,
s4