I use Knoppix mostly as a tool to help TC when I want to look into hardware issues and so forth.
But, the touchpad can be an issue for some, so here's a quickstart on how to get the touchpad working.
After boot, bring up a terminal. Normally I have to use the left-side key on the touchpad to launch the terminal initially.
At the prompt to enable tapping the touchpad. Unlike the other lines, don't forget to specify the first button AND make it true (1=1)
synclient TapButton1=1
To enable the vertical edge scroll (if your pad has it)
synclient VertEdgeScroll=1
If you have a horizontal bottom edge scroll left and right:
synclient HorizEdgeScroll=1
If you have persistence, you can save these so they work upon boot. Just add these commands to your
/etc/X11/Xsession.d/45knoppix
Tip: the "no3d" cheatcode does not work for some. To get it to work, edit your boot stanza, rather than manually passing the cheat at boot time.