By the way, I'm currently on 7.x where the intel graphics driver is broken for 3D (in my case). However, on 5.x & 6.x I used to play AoE2, Diablo2 and Quake2 through WINE, and Doom (Zandronum), zSNES and Minecraft natively. Also several other SDL games. So it's possible in general.
Tiny Core is no anti-gaming platform. Even if it is not TC's goal, you can make it a gaming station. As usual though, a nvidia card and it's proprietary drivers are probably preferable regarding 3D.
I couldn't get the Freespace SCP client to compile, but IIRC that was a perl version incompatibility.